Scientist II, QSP/QST Consulting Services

Job Description:

• Design, write, test, and use computer code to build and maintain sub-models representing cellular, molecular, and/or biochemical processes
• Represent compound pharmacodynamics and/or mechanism of action, translating laboratory data into model parameters and curating clinical data for calibration and validation
• Learn and utilize company agentic AI solutions for technical work
• Contribute to successful completion of consulting project goals
• Contribute to R&D efforts, including license-ready model updates and development of QST models of liver injury
• Combine systems pharmacology modeling, software code development, maintenance, and project management
• Develop plans and deliverables consistent with sponsor service agreements
• Schedule meetings with internal and external collaborators
• Prepare presentations and reports, conduct scientific review, and respond to feedback
• Lead consulting projects when qualified and available
• Participate in preparation and review of joint manuscripts
• Manage project effort within contracted resources
• Publish scientific work, including documentation, figures, and correspondence with editors and peer reviewers
• Train others on QSP/QST and related models
• Perform other duties as assigned

Requirements:

• 2+ years of QSP/QST modeling experience or equivalent skill sets
• Proficiency in mathematics, dynamic systems, and drug development
• General knowledge of relevant therapeutic areas, clinical endpoints, and underlying cell and molecular biology and/or biochemistry
• Experience with MATLAB, THALES, Julia, SimBiology, Monolix, GastroPlus™, and/or C++ programming
• Experience with PBPK, PK, popPK, and/or PKPD modeling
• Basic familiarity with large-language models and agentic AI
• Understanding of how to apply modeling and simulation for maximum impact
• Strong verbal and written communication skills
• Ability to multitask and good organizational skills
• Self-motivated with ability to work with minimal supervision
• Occasional travel for conferences, meetings, and training
• Master’s degree in pharmaceutical science, biomedical engineering, or related field required
• PhD in pharmaceutical science, biomedical engineering, or related field preferred

Benefits:

• Fully remote work
• Flexible schedules
• Generous vacation policy
• Affordable health coverage
• Annual bonus
• Employee well-being programs
• Opportunities to publish work in scientific journals
• Professional training and development opportunities